Telomeres, cellular senescence and NAD-related research.
What to look for. Cellular pathways help explain research interest; the studies here do not establish a human lifespan benefit.
Epithalon, also called Epitalon, is studied for effects on telomere-maintenance pathways. Its aging-related appeal comes from questions about how cells maintain chromosome ends; the cited work tests normal and cancer cell lines.
Evidence in this guide: Cell-line telomerase and alternative telomere-maintenance experiments.
Read the Epithalon guide ↗Humanin is a mitochondria-derived peptide studied in cellular stress responses. Researchers examine how mitochondrial signaling changes in aging cells, including senescent human fibroblasts.
Evidence in this guide: Cellular senescence and mitochondrial-function research.
Read the Humanin guide ↗NAD+ is a coenzyme used in energy transfer and cellular redox reactions. Wellness providers discuss fatigue and healthy-aging goals; the linked human IV pilot measured metabolites during an infusion rather than clinical anti-aging outcomes.
Evidence in this guide: Cell biology, a small human IV metabolism study and named provider schedules.
