YOUR COMPOUND / YOUR QUESTIONS

SS-31.

SS-31, or elamipretide, is researched for effects on mitochondrial function. The prescription product Forzinity received accelerated US approval to improve muscle strength in people with Barth syndrome weighing at least 30 kg.

Research focus: Mitochondrial function and Barth-syndrome muscle strength.

Narrow, product-specific approved indicationSources checked October 6, 2026
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Choose a compound to open its research, documentation and calculator.

QUICK REFERENCE

The essentials.

Checked October 15, 2026
FDA status
FDA status and scope

Forzinity: accelerated approval for muscle strength in Barth syndrome, weight at least 30 kg.

Official source ↗
FDA-approved product
Half-life
Half-life: source and route

Elamipretide pharmacokinetics in the Forzinity development program.

Half-life describes concentration falling by half. It does not set a dosing interval, a storage period or a drug-test detection window.

Kinetics source ↗
0.6–1.5 hoursHuman · FDA clinical review
Diluent / formulation
Diluent and formulation

Community preparation guides describe BAC (bacteriostatic) water for lyophilized SS-31 research vials. This is separate from Forzinity, the approved elamipretide product supplied as a ready-made solution that is not reconstituted.

Bacteriostatic water contains a preservative; plain sterile water does not. Preservative presence does not by itself establish compatibility or a mixed medicine’s usable period.

Preparation source ↗
BAC water · research vialsCommunity-reported · lyophilized powder
START WITH THE EVIDENCE

What the documentation tells us.

Evidence context

The label instructions below apply to the named prescription products and their indications. A matching peptide name on another vial does not establish an equivalent formulation.

Check that a source concerns the same molecule, formulation, route and population. A study of cells, animals or a different product cannot confirm the contents of a vial.

A narrow approved indication; broad healthy-aging uses are a different research question.

Other names you may encounter: Elamipretide.

Learn to read a study →
DOSAGE & SCHEDULE CONTEXT

Community schedules and research routes.

Dosage & schedule options.

Reading these schedules

Each entry keeps one schedule’s amount, frequency and cycle together. Community references, individual reports, clinical trials and prescription products describe different kinds of use. A missing duration or break stays marked as not reported.

Amounts describe mass in mg or mcg. Syringe units describe volume and depend on concentration. A cycle break is different from days off within a week.

Choose an option to explore its amounts, timing and cycle.

Prescription productForzinity · Barth syndrome treatmentSubcutaneousOngoing prescribed treatment for the labeled indication

Dose
40 mg per injection; renal adjustment applies in adults
How often
Once daily, at the same time each day
Route
Subcutaneous
Duration
Ongoing prescribed treatment for the labeled indication
Break after cycle
No scheduled cycle break in the label

For adults with eGFR <30 mL/minute who are not on dialysis: the label specifies 20 mg daily. Dialysis instructions are not established. This is not a general healthy-aging regimen.

Individual community reportDaily use before MOTS-c · individual accountNot reported10–20 days

Dose
4 mg per day
How often
Daily
Route
Not reported
Duration
10–20 days
Break after cycle
Not reported

MOTS-c followed as a separate phase in this account.

Individual community reportGradual daily increases · individual logNot reported16-day log

Dose
1 mg daily initially; rising to 4 mg daily
How often
Daily
Route
Not reported
Duration
16-day log
Break after cycle
Not reported
Dose changes within this protocol
WhenAmount & frequency
Days 1–41 mg daily
Day 72 mg daily
Days 9–113 mg daily
Days 12–164 mg daily

Only explicitly recoverable amounts are shown. Unlisted days are not assigned an inferred amount.

Reconstitution & storage ↓
FORMULATION FIRST

Reconstitution, storage and devices.

Product-specific handling

A peptide name and vial mass cannot determine a compatible diluent, powder displacement, storage temperature or discard date. Follow the exact product’s instructions and your pharmacist’s directions.

The injection guide concerns clinician-prescribed subcutaneous medicines; it does not establish that a research-labeled material can be injected.

Start with the formulation: dry powder, prepared solution, pen, tablet and topical product can have different instructions.

Storage: before and after opening.

US product label

Forzinity · prescription elamipretide vial

Before opening
Refrigerate at 2–8°C (36–46°F). Do not freeze.
After mixing / first use
After first dose: refrigerate at 2–8°C or store at 20–25°C (68–77°F). Discard 8 days after first opening.
Handling & discard
Ready-to-use prescription solution. This eight-day rule does not establish storage for a separate SS-31 powder.
Forzinity · storage section ↗
THE EVERYDAY CONTEXT

Habits & tracking that help.

General health habits and consistent observations help you assess changes. They are not evidence that a peptide’s effects will be amplified.

Include movement and strength work

Choose activity that fits your health and ability. Aerobic movement and muscle-strengthening work are part of general adult activity guidance.

CDC · adult activity ↗

Keep a consistent sleep routine

Use a regular sleep/wake schedule and note changes in sleep quality alongside symptoms or training.

CDC · sleep habits ↗

What to record: Choose measurable goals such as day-to-day function, exercise tolerance or symptoms. A cellular biomarker is different from a demonstrated improvement in health or lifespan.

GO TO THE ORIGINAL

Documentation behind SS-31.

About source checks

Check dates are editorial references, not a medical review certificate. Labels and evidence can change; consult the linked current document.

THE MATH, EXPLAINED

SS-31 calculator.

About calculator examples

Opening values and worked examples illustrate arithmetic; they are not preparation instructions or recommended amounts. Selecting a compound labels the calculation and does not supply a dose or powder-volume correction.

Enter the documented vial mass, preparation information and target amount to see how mass and volume connect.

An arithmetic example

20 mg in an assumed final 1 mL gives 20 mg/mL. An entered 1 mg corresponds to 0.05 mL, or 5 U-100 units, with 20 theoretical portions before losses.

YOUR CALCULATION WORKSPACE

Three tools. Clear numbers.

Open focused view →
01 / YOUR INPUTS

Vial → dose → syringe

mg
mL
Slider range: 1 to 20 mg, in 1 mg steps. Click a labeled value to select it. Type exact decimal amounts in the field above.
Advanced Volume & syringe settings
02 / YOUR RESULTCalculated

SS-31

Estimate · assumes 1 mL added = total volume

U-100 syringe1 mL capacity · 100 units
Amount per dose
1 mg

1,000 mcg

Full doses per vial
5

Theoretical · before losses

Syringe amount per dose
20units

0.2 mL

Amount remaining
0 mg

After 5 full doses

U-100 volume scale

Illustration only · calculated value, without rounding

Concentration & remaining liquid
Concentration
5 mg/mL
Per U-100 unit
50 mcg
Full portions in vial
5
Theoretical remainder
0 mL

Saved calculations stay on this device.

See the calculation

Concentration = mass ÷ final volume

5 mg ÷ 1 mL = 5 mg/mL

Volume = target mass ÷ concentration

1 mg ÷ 5 mg/mL = 0.2 mL

U-100 markings = volume × 100

0.2 mL × 100 = 20 units

Complete portions = floor(vial mass ÷ amount per portion).

Displayed numbers are rounded for readability; the calculation uses unrounded values.

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