YOUR COMPOUND / YOUR QUESTIONS

PT-141.

PT-141, or bremelanotide, is a melanocortin-receptor agonist. The prescription product Vyleesi treats acquired, generalized hypoactive sexual desire disorder in eligible premenopausal women; broader libido claims need their own evidence.

Research focus: Sexual desire in a defined clinical population.

Product-specific prescribing informationSources checked October 6, 2026
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Choose a compound to open its research, documentation and calculator.

QUICK REFERENCE

The essentials.

Checked October 15, 2026
FDA status
FDA status and scope

Vyleesi: acquired, generalized HSDD in eligible premenopausal women.

Official source ↗
FDA-approved product
Half-life
Half-life: source and route

Mean terminal half-life after a single subcutaneous dose; reported range 1.9–4.0 hours.

Half-life describes concentration falling by half. It does not set a dosing interval, a storage period or a drug-test detection window.

Kinetics source ↗
About 2.7 hoursHuman · Vyleesi label
Diluent / formulation
Diluent and formulation

Approved injections are supplied as solutions; do not add diluent. Tablets are not mixed. A separately supplied powder requires its own formulation documentation.

Bacteriostatic water contains a preservative; plain sterile water does not. Preservative presence does not by itself establish compatibility or a mixed medicine’s usable period.

Preparation source ↗
Ready-to-use approved productsProduct labels
START WITH THE EVIDENCE

What the documentation tells us.

Evidence context

The label instructions below apply to the named prescription products and their indications. A matching peptide name on another vial does not establish an equivalent formulation.

Check that a source concerns the same molecule, formulation, route and population. A study of cells, animals or a different product cannot confirm the contents of a vial.

Product-specific human evidence and US prescribing information.

Other names you may encounter: Bremelanotide.

Learn to read a study →
DOSAGE & SCHEDULE CONTEXT

Community schedules and research routes.

Dosage & schedule options.

Reading these schedules

Each entry keeps one schedule’s amount, frequency and cycle together. Community references, individual reports, clinical trials and prescription products describe different kinds of use. A missing duration or break stays marked as not reported.

Amounts describe mass in mg or mcg. Syringe units describe volume and depend on concentration. A cycle break is different from days off within a week.

Choose an option to explore its amounts, timing and cycle.

Prescription productVyleesi · on-demand injectionsSubcutaneousReassess at 8 weeks; discontinue if symptoms have not improved

Dose
1.75 mg per single-dose autoinjector
How often
As needed; no more than 1 dose in 24 hours
Route
Subcutaneous
Duration
Reassess at 8 weeks; discontinue if symptoms have not improved
Break after cycle
No calendar cycle; more than 8 doses/month is not recommended
Time of day
At least 45 minutes before anticipated sexual activity

Contraindicated with uncontrolled hypertension or known cardiovascular disease. These instructions apply to the named prescription product.

Individual community reportOn-demand use · individual attemptsInjected; injection type not reportedNot reported

Dose
1–1.75 mg across separate attempts
How often
On demand; intervals not fully reported
Route
Injected; injection type not reported
Duration
Not reported
Break after cycle
Not reported

These amounts belong to different attempts and individuals, rather than repeated administrations on one day.

Reconstitution & storage ↓
FORMULATION FIRST

Reconstitution, storage and devices.

Product-specific handling

A peptide name and vial mass cannot determine a compatible diluent, powder displacement, storage temperature or discard date. Follow the exact product’s instructions and your pharmacist’s directions.

The injection guide concerns clinician-prescribed subcutaneous medicines; it does not establish that a research-labeled material can be injected.

Start with the formulation: dry powder, prepared solution, pen, tablet and topical product can have different instructions.

Storage: before and after opening.

US product label

Vyleesi · single-dose autoinjector

Before opening
Store at or below 25°C (77°F), protected from light.
After mixing / first use
Use immediately after removing the cap; dispose of the autoinjector after use.
Handling & discard
Do not freeze. These instructions apply to Vyleesi, not a separate research powder.
Vyleesi · storage & device instructions ↗
THE EVERYDAY CONTEXT

Habits & tracking that help.

General health habits and consistent observations help you assess changes. They are not evidence that a peptide’s effects will be amplified.

Include movement and strength work

Choose activity that fits your health and ability. Aerobic movement and muscle-strengthening work are part of general adult activity guidance.

CDC · adult activity ↗

Keep a consistent sleep routine

Use a regular sleep/wake schedule and note changes in sleep quality alongside symptoms or training.

CDC · sleep habits ↗

What to record: Discuss the specific concern, other medicines and relevant health conditions with the treating clinician; the goal and eligible population matter.

GO TO THE ORIGINAL

Documentation behind PT-141.

About source checks

Check dates are editorial references, not a medical review certificate. Labels and evidence can change; consult the linked current document.

THE MATH, EXPLAINED

PT-141 calculator.

About calculator examples

Opening values and worked examples illustrate arithmetic; they are not preparation instructions or recommended amounts. Selecting a compound labels the calculation and does not supply a dose or powder-volume correction.

Enter the documented vial mass, preparation information and target amount to see how mass and volume connect.

An arithmetic example

20 mg in an assumed final 1 mL gives 20 mg/mL. An entered 1 mg corresponds to 0.05 mL, or 5 U-100 units, with 20 theoretical portions before losses.

YOUR CALCULATION WORKSPACE

Three tools. Clear numbers.

Open focused view →
01 / YOUR INPUTS

Vial → dose → syringe

mg
mL
Slider range: 1 to 20 mg, in 1 mg steps. Click a labeled value to select it. Type exact decimal amounts in the field above.
Advanced Volume & syringe settings
02 / YOUR RESULTCalculated

PT-141

Estimate · assumes 1 mL added = total volume

U-100 syringe1 mL capacity · 100 units
Amount per dose
1 mg

1,000 mcg

Full doses per vial
5

Theoretical · before losses

Syringe amount per dose
20units

0.2 mL

Amount remaining
0 mg

After 5 full doses

U-100 volume scale

Illustration only · calculated value, without rounding

Concentration & remaining liquid
Concentration
5 mg/mL
Per U-100 unit
50 mcg
Full portions in vial
5
Theoretical remainder
0 mL

Saved calculations stay on this device.

See the calculation

Concentration = mass ÷ final volume

5 mg ÷ 1 mL = 5 mg/mL

Volume = target mass ÷ concentration

1 mg ÷ 5 mg/mL = 0.2 mL

U-100 markings = volume × 100

0.2 mL × 100 = 20 units

Complete portions = floor(vial mass ÷ amount per portion).

Displayed numbers are rounded for readability; the calculation uses unrounded values.

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